Complementary Photocatalytic Toolbox: Control of Intramolecular endo- versus exo-trig Cyclizations of α-Phenyl Olefins to Oxaheterocyclic Products
نویسندگان
چکیده
Abstract The regioselectivity of the intramolecular cyclization bifunctional α-phenyl alkenes can be controlled simply by choice organic chromophore as photocatalyst. central photoredox catalytic reaction in both cases is a nucleophilic addition hydroxy function to olefin substrates. N,N-(4-Diisobutylaminophenyl)phenothiazine catalyzes exo-trig cyclizations, whereas 1,7-dicyanoperylene-3,4,9,10-tetracarboxylic acid bisimides catalyze endo-trig additions products with anti-Markovnikov regioselectivity. We preliminarily report conversions 11 representative substrates into 20 oxaheterocycles order demonstrate similarity, but also complementarity, these two variants this toolbox.
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ژورنال
عنوان ژورنال: Synlett
سال: 2022
ISSN: ['0936-5214', '1437-2096']
DOI: https://doi.org/10.1055/s-0040-1719871